Welcome to the protein NMR pH titration database. NMR-monitored pH titration experiments are routinely used to measure site-specific protein pKa values. Accurate experimental pKa values are essential in dissecting enzyme catalysis, in studying the pH-dependence of protein stability and ligand binding and ultimately in understanding electrostatic effects in proteins. It is therefore important to retain the raw NMR spectroscopic data to allow for possible reinterpretation.

Is a repository of information relative to the nomenclature of enzymes. By search in comments lines.

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